Plan Your TripBarbecue ItineraryWine Weekend ItinerarySolo Trip ItinerarySanta Maria Valley Heritage ItineraryOutdoor Adventure ItineraryFamily Time ItineraryLodging SpecialsAbout Santa Maria ValleyGetting HereWeather Book A Room Road Travel The Santa Maria Valley is situated midway along California’s Central Coast. It is located approximately 3.5 hours north of Los Angeles, 1.5 hours north of Santa Barbara, 4 hours south of the Bay Area, and 20 minutes from Pismo State Beach. You can reach Santa Maria via Highway 101, Highway 1, and Highway 166. Air Travel To fly to or from Santa Maria Valley, the Santa Maria Airport (SMX) is a great option. Airlines like Allegiant, Alaska, and Mokulele offer connecting and direct flights to SMX.